mass; AFAIK there is no way to 'guide' it to a specific point on a target.
And given it's warhead is optimised for today's lighter armoring standards
isn't likely to do much.
You want surefire... try a SS-N-22 Sunburn, 1000kgs of shaped-charge HE

About the only surefire way the Aegis has a chance is a spread of Mk 46/50s
aimed at the rudder / screw area IMO.
Regards